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Mounjaro vs Wegovy

Mounjaro vs. Wegovy: A Simple Comparison

 

Both Mounjaro (tirzepatide) and Wegovy (semaglutide) are highly effective, once-weekly injectable treatments for obesity. While both restrict appetite and aid significant weight loss, the difference in how they work and their proven effectiveness can help guide your decision.

 

That’s an important addition. Adding common adverse effects to the table provides a direct side-by-side comparison that patients need when evaluating treatments.

I have updated the table to include a row for Most Common Adverse Events and adjusted the article accordingly.

 

Mounjaro vs. Wegovy: What Weight Loss Can You Really Expect?

 

Both Mounjaro (tirzepatide) and Wegovy (semaglutide) are potent medications that lead to significant weight reduction. We’ve broken down the key clinical trial results and what it means for your long-term success.

 

Feature Mounjaro (Tirzepatide) Wegovy (Semaglutide)
Primary Action Dual Hormone Agonist (GLP-1 & GIP) Single Hormone Agonist (GLP-1)
How It Works (Simple) Mimics two appetite hormones. Mimics one appetite hormone.
Average Weight Loss -22.5% of starting body weight (highest dose) -15% of starting body weight (highest dose)
Most Common Adverse Events Nausea, Diarrhoea, Vomiting, Constipation, Abdominal Pain Nausea, Diarrhoea, Vomiting, Constipation, Abdominal Pain
Administration Method Pre-filled, concealed needle pen Pre-filled, concealed needle pen
Dose Increase Schedule Typically every 4 weeks Typically every 4 weeks
Secondary Benefit Significantly lowers A1C (blood sugar) and is licensed for Type 2 Diabetes. May reduce major adverse cardiovascular events (MACE) in certain high-risk patients.
Impact on Diabetes Licensed for Type 2 Diabetes treatment. Not licensed for Type 2 Diabetes treatment.
Typical Monthly Price* £240 £95

 

All in all they are very similar drugs and both are very effective at increasing weight loss. See our page on how much weight you can lose?

 

Note: Prices are estimates, please see our pricing table to get the best & latest offers!

 

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Compare Wegovy and Mounjaro providers

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WegovyNumanFrom£65HC rating8.8WegovyNumanFrom£95HC rating8.8MounjaroNumanFrom£145HC rating8.8
MounjaroNumanFrom£175HC rating8.8
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